Welcome to the FIT for Follow-Up study website!

The information on this website is intended for people who took part in the FIT for Follow-Up study.  

The aim of the study was to establish whether Faecal Immunochemical Testing (FIT) could be an effective alternative to colonoscopy surveillance for finding large polyps in the bowel. 

We hope the results of the FIT for Follow-Up study will be available later this year. If you were a study participant and would like to receive a copy of the results when they become available, CLICK HERE.


About the FIT for Follow-Up study

The NHS Bowel Cancer Screening Programme recommends that people who have a large polyp, or a few small polyps, removed at their first colonoscopy should come back in three years for a ‘rescope’ – another colonoscopy to check for any further polyps that may have grown in the large bowel.

If you were living in England, had a colonoscopy through the NHS Bowel Cancer Screening Programme, and were advised that you should return for a second colonoscopy in three years’ time, you may have been invited to take part in the FIT for Follow-Up study.

People who agreed to participate in the FIT for Follow-Up study were asked to complete a Faecal Immunochemical Test (FIT) once a year for three years.

If the FIT test taken in years 1 or 2 found traces of blood, participants were invited to attend an early colonoscopy at their usual bowel screening centre. At the end of year 3, everyone was invited to attend the follow-up colonoscopy recommended by the NHS Bowel Cancer Screening Programme.

A total of 8009 people were invited to participate in the study. 5953 (73%) of those people returned a signed consent form and the FIT kit, and were later told the results of their first round of FIT testing.

A year later 5494 participants were sent a second FIT kit. 5296 (96%) of people completed their second FIT, and kindly returned this to us for laboratory processing.

We have just completed the third round of FIT testing. 5256 people were sent their third and final FIT kit, and 5057 (96.2%) of people returned a completed test to us. Alongside these FIT tests you have also been kind enough to fill in patient experience questionnaires, which help us improve the FIT kit instructions, and health and lifestyle questionnaires, that tell us more about the study participants so we can better understand the FIT kit results.

Remember that the aim of the FIT for Follow-Up study is to find out whether FIT testing is accurate enough to replace colonoscopy surveillance. We don’t know the answer to this question yet, so it’s important that you still have your colonoscopy regardless of the result of your FIT test.

If you would like further information please see our Frequently Asked Questions (FAQs).

This study is funded by the Health Technology Assessment Programme, part of the NHS National Institute for Health Research

It is run jointly by the NHS Bowel Cancer Screening Southern Programme Hub, Imperial College and University College London. Imperial College is the sponsor of the study.